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Now Enrolling
Research of an investigational 24-valent
pneumococcal vaccine for healthy infants
pneumococcal vaccine for healthy infants
Streptococcus pneumoniae (S. pneumoniae)
is a leading cause of human disease
is a leading cause of human disease
AFX3772 aims to protect against 24 of its pneumococcal serotypes
As you know, S. pneumoniae is a major contributor of illness ranging from the common, such as acute otitis media, to the serious, such as meningitis and bacteremia. Its polysaccharide (PS) encapsulation leads to a strong and potentially threatening virulence.
AFX3772 is designed to
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Carry 24 serotypes of S. pneumoniae
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Contain a unique protein created by the fusion of pneumococcal proteins, sp1500 and sp0785
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Induce B- and T-cell responses to pneumococcal PS and proteins
AFX3772 aims to provide broad and durable extended protection against S. pneumoniae.
The study of AFX3772 is a Phase 2, proof-of-concept study to support advancement of AFX3772 into Phase 3 pediatric clinical development.
This study is:
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Randomized and double-blind
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Evaluating the safety, tolerability, and immunogenicity of different dose levels of AFX3772
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Currently enrolling patients
Download and share the study brochure with your patients.
Who can participate in this study?
Patients who meet the following criteria may qualify:
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Healthy, full-term infants (≥ 37 weeks gestation at birth)
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Approximately 2 months of age (42 to 90 days, inclusive)
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Naïve to any pneumococcal vaccine
This is not a complete list of criteria. Click to see the full eligibility criteria.
Study Summary
Study Drug:
AFX3772, an investigational pneumococcal vaccine
Participant Details:
Healthy infants, 42 to 90 days of age (inclusive)
Sponsor
Enrollment Period:
Currently enrolling
PLEASE SCAN THE QR CODE
TO SHARE THE PATIENT WEBSITE LINK WITH YOUR PATIENTS.
TO SHARE THE PATIENT WEBSITE LINK WITH YOUR PATIENTS.
Copy the patient website link into your patient notes.
Study Site Locations
Click on the map below for study site locations near you and their contact information.
Location
Click to copy and paste nearby study site locations into your patient notes.
